{"id":111,"date":"2025-04-15T12:19:48","date_gmt":"2025-04-15T03:19:48","guid":{"rendered":"http:\/\/dgprt.brc.riken.jp\/ja\/?page_id=111"},"modified":"2025-04-15T12:19:48","modified_gmt":"2025-04-15T03:19:48","slug":"publication","status":"publish","type":"page","link":"http:\/\/dgprt.brc.riken.jp\/ja\/publication\/","title":{"rendered":"\u696d\u7e3e"},"content":{"rendered":"<div id=\"pl-111\"  class=\"panel-layout\" ><div id=\"pg-111-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-111-0-0\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><div id=\"pgc-111-0-1\"  class=\"panel-grid-cell panel-grid-cell-mobile-last\" ><div id=\"panel-111-0-1-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div id=\"publication\" class=\"panel-widget-style panel-widget-style-for-111-0-1-0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<ul>\n<li>Otsuka K., Sakashita A., Maezawa S., Schultz RM., Namekawa SH.<br \/>\n      KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptome and genome evolution.<br \/>\n      <i>Genome Res<\/i>. Mar 12;35(3):417-431. (2025)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40074296\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/genome.cshlp.org\/content\/35\/3\/417.long\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Guo Y., Kitano T., Inoue K., Murano K., Hirose M., Li TD., Sakashita A., Ishizu H., Ogonuki N., Matoba S., Sato M., Ogura A., Siomi H.<br \/>\n      Obox4 promote zygotic genome activation upon loss of Dux.<br \/>\n      <i>Elife<\/i> Jun10:13:e95856. (2024)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38856708\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/elifesciences.org\/articles\/95856\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, Namekawa SH.<br \/>\n      Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin.<br \/>\n      <i>Nucleic Acids Res<\/i>. Jul 21;51(13):6668-6683. (2023)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37283086\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/academic.oup.com\/nar\/article\/51\/13\/6668\/7191436\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A, Kitano T, Ishizu H, Guo Y, Masuda H, Ariura M, Murano K, Siomi H.<br \/>\n      Transcription of MERVL retrotransposons is required for preimplantation embryo development.<br \/>\n      <i>Nat Genet<\/i>. Mar;55(3):484-495. (2023)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36864102\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/www.nature.com\/articles\/s41588-023-01324-y\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A, Takeuchi C, Maezawa S, Namekawa SH.<br \/>\n      Bioinformatics Pipelines for Identification of Super-Enhancers and 3D Chromatin Contacts.<br \/>\n      <i>Methods Mol Biol<\/i>. : 2577:123-146. (2023)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36173570\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/link.springer.com\/protocol\/10.1007\/978-1-0716-2724-2_9\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A., Ariura M., Namekawa SH.<br \/>\n      CRISPR-mediated activation of transposable elements in embryonic stem cell.<br \/>\n      <i>Methods Mol Biol<\/i>. ;2509:171-194. (2022)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35796964\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/link.springer.com\/protocol\/10.1007\/978-1-0716-2380-0_11\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A, Maezawa S, Takahashi K, Alavattam KG, Yukawa M, Hu YC, Kojima S, Parrish NF, Barski A, Pavlicev M, Namekawa SH.<br \/>\n      Endogenous retroviruses drive species-specific germline transcriptomes in mammals.<br \/>\n      <i>Nat Struct Mol Biol<\/i>.; 27(10):967-977. (2020)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32895553\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/www.nature.com\/articles\/s41594-020-0487-4\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Maezawa S, Sakashita A, Yukawa M, Chen X, Takahashi K, Alavattam KG, Nakata I, Weirauch MT, Barski A, Namekawa SH.<br \/>\n      Super-enhancer switching drives a burst in gene expression at the mitosis-to-meiosis transition.<br \/>\n      <i>Nat Struct Mol Biol<\/i>.; 27(10):978-988. (2020)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32895557\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/www.nature.com\/articles\/s41594-020-0488-3\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Sakashita A, T Wakai, Y Kawabata, C Nishimura, Y Sotomaru, KG Alavattam, Namekawa SH, Kono T.<br \/>\n      XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage.<br \/>\n      <i>Biol Reprod<\/i>.; 100(3):697-710. (2019)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30289439\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/academic.oup.com\/biolreprod\/article\/100\/3\/697\/5115558\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<li>Alavattam KG, Maezawa S, Sakashita A, Khoury H, Barski A, Kaplan N, Namekawa SH.<br \/>\n      Attenuated chromatin compartmentalization in meiosis and its maturation in sperm development.<br \/>\n      <i>Nat Struct Mol Biol<\/i>.; 26(3):175-184. (2019)<br \/>\n      [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30778237\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>]&nbsp;[<a href=\"https:\/\/www.nature.com\/articles\/s41594-019-0189-y\" target=\"_blank\" rel=\"noopener\">Journal<\/a>]<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pgc-111-0-2\"  class=\"panel-grid-cell panel-grid-cell-empty\" ><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Otsuka K., Sakashita A., Maezawa S., Schultz RM., Namekawa SH. KRAB-zinc-finger proteins regulate endogenous r&hellip;<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-111","page","type-page","status-publish","hentry","post"],"_links":{"self":[{"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=111"}],"version-history":[{"count":0,"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/111\/revisions"}],"wp:attachment":[{"href":"http:\/\/dgprt.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}